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Fibrinogen γ-chain (117-133)

Product Specifications

CAS Number

160927-63-9

Target

Integrin

Related Pathways

Cytoskeletal Signaling

Bioactivity

Fibrinogen γ-chain (117-133) is a selective inhibitor of intercellular adhesion molecule-1 (ICAM-1), with an IC50 of approximately 20-40 μg/mL. It can block fibrinogen-mediated adhesion of monocytes to endothelial cells and shows potential for research in thrombo-inflammatory diseases, such as atherosclerosis and organ transplant rejection.

Smiles

[C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(N)=O)N)=O)CC(N)=O)=O)CCC(N)=O)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(N)=O)=O)C)=O)C(C)C)=O)CCCCN)=O)CCC(O)=O)=O)CCCCN)=O)CC(C)C)=O)CC(N)=O)=O)C(C)C)=O)[C@H](CC)C)=O)CCCCN

Molecular Formula

C84H147N25O27

Molecular Weight

1939.22

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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