Fibrinogen γ-chain (117-133)
Product Specifications
CAS Number
160927-63-9
Target
Integrin
Related Pathways
Cytoskeletal Signaling
Bioactivity
Fibrinogen γ-chain (117-133) is a selective inhibitor of intercellular adhesion molecule-1 (ICAM-1), with an IC50 of approximately 20-40 μg/mL. It can block fibrinogen-mediated adhesion of monocytes to endothelial cells and shows potential for research in thrombo-inflammatory diseases, such as atherosclerosis and organ transplant rejection.
Smiles
[C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(N)=O)N)=O)CC(N)=O)=O)CCC(N)=O)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(N)=O)=O)C)=O)C(C)C)=O)CCCCN)=O)CCC(O)=O)=O)CCCCN)=O)CC(C)C)=O)CC(N)=O)=O)C(C)C)=O)[C@H](CC)C)=O)CCCCN
Molecular Formula
C84H147N25O27
Molecular Weight
1939.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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