P9R

P9R is an antiviral peptide with broad-spectrum activity against coronaviruses (SARS-CoV-2, MERS-CoV, and SARS-CoV), influenza A H1N1 virus (A (H1N1) pdm09), influenza A H7N9 virus (A (H7N9) virus), and rhinovirus. It binds directly to viruses and inhibits virus-host endosomal acidification. P9R significantly protects mice from infection by influenza A H1N1 virus (A (H1N1) pdm09) without leading to resistant viruses. P9R is applicable in studying pH-dependent respiratory viruses.

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