Tat-IKIP (46-60)
Product Specifications
Target
NF-?B|||I?B/IKK
Related Pathways
NF-?B
Bioactivity
Tat-IKIP (46-60) is a transmembrane peptide that targets I?B kinase (IKK) . It inhibits the activation of IKK and the expression of NF-?B target genes by disrupting the IKK?/NEMO complex. In mouse models, Tat-IKIP (46-60) significantly alleviates DSS-induced acute inflammation in inflammatory bowel disease (IBD) and reduces zymosan-induced acute arthritis in acute arthritis models (AAM) . This compound is applicable in research on inflammatory diseases such as IBD, pancreatitis, and rheumatoid arthritis.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/390881981229482197/TP3801
Available Sizes
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