Tat-IKIP (46-60)
Product Specifications
Target
NF-?B|||I?B/IKK
Related Pathways
NF-?B
Bioactivity
Tat-IKIP (46-60) is a transmembrane peptide that targets I?B kinase (IKK) . It inhibits the activation of IKK and the expression of NF-?B target genes by disrupting the IKK?/NEMO complex. In mouse models, Tat-IKIP (46-60) significantly alleviates DSS-induced acute inflammation in inflammatory bowel disease (IBD) and reduces zymosan-induced acute arthritis in acute arthritis models (AAM) . This compound is applicable in research on inflammatory diseases such as IBD, pancreatitis, and rheumatoid arthritis.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
