Corza6 TFA
Product Specifications
Target
ROS|||Proton pump
Related Pathways
Immunology/Inflammation|||Membrane transporter/Ion channel
Bioactivity
Corza6 TFA is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1) . It binds to the external voltage-sensor domain (VSD) loop of hHv1 with a dissociation constant (Kd) of approximately 1 nM under the native hyperpolarized resting membrane potential (RMP) of mammalian cells. Additionally, Corza6 TFA induces sperm capacitation and enables continuous reactive oxygen species (ROS) production in white blood cells (WBC) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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