Z-Val-Val-Nle-diazomethylketone
Product Specifications
Target
Cysteine Protease|||MHC
Related Pathways
Immunology/Inflammation|||Proteases/Proteasome
Bioactivity
Z-Val-Val-Nle-diazomethylketone is an inhibitor of cathepsin S (CATS) . It significantly suppresses the upregulation of IFNg-induced MHCII molecules, specifically HLA-DR and Ii-p33/35, while increasing the protein level of Ii-p10. This compound can be utilized for research into skin disorders such as psoriasis, atopic dermatitis, and actinic keratosis.
Smiles
[C@@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)C(C)C)=O)[C@@H](C)C)=O)(C(C=[N+]=[N-])=O)CCCC
Molecular Formula
C25H37N5O5
Molecular Weight
487.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/390881260870352975/TP3771
CAS Number
155026-49-6
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15248823 1 Vial
Lentiviral mouse Ucn2 shRNA (UAS) - Lentiviral mouse Ucn2 shRNA (UAS, iRFP) (100)
Ask
View Details GTR15112006 1 Vial
Lentiviral mouse Cry1 shRNA (UAS) - Lentiviral mouse Cry1 shRNA (UAS, GFP) plasmid
Ask
View Details NBP3-28486-50ug 50 µg
CHO Monoclonal DR6/TNFRSF21 Antibody (Abbvie patent anti-TNFRSF21) - Humanized - (Dry Ice)
Ask
View Details 