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YVPGP

Product Specifications

CAS Number

2095286-57-8

Target

PI3K, Apoptosis, Caspase, Akt, Bcl-2 Family, mTOR

Related Pathways

Proteases/Proteasome, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis

Bioactivity

YVPGP is an oligopeptide extracted from Anthopleura anjunae. It exhibits significant anti-tumor activity by mediating the PI3K/AKT/mTOR signaling pathway. YVPGP can arrest DU-145 cells in the S phase and induce apoptosis (apoptosis) through mitochondrial and death receptor pathways (caspase3, 7, 8, 9) . It effectively inhibits tumor growth in a DU-145 xenograft mouse model, showing potential for prostate cancer research.

Smiles

C([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)[C@H](C)C)(=O)N2[C@H](C(NCC(=O)N3[C@H](C(O)=O)CCC3)=O)CCC2

Molecular Formula

C26H37N5O7

Molecular Weight

531.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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