YVPGP
Product Specifications
CAS Number
2095286-57-8
Target
PI3K|||Apoptosis|||Caspase|||Akt|||Bcl-2 Family|||mTOR
Related Pathways
Proteases/Proteasome|||PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling|||Apoptosis
Bioactivity
YVPGP is an oligopeptide extracted from Anthopleura anjunae. It exhibits significant anti-tumor activity by mediating the PI3K/AKT/mTOR signaling pathway. YVPGP can arrest DU-145 cells in the S phase and induce apoptosis (apoptosis) through mitochondrial and death receptor pathways (caspase3, 7, 8, 9) . It effectively inhibits tumor growth in a DU-145 xenograft mouse model, showing potential for prostate cancer research.
Smiles
C([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)[C@H](C)C)(=O)N2[C@H](C(NCC(=O)N3[C@H](C(O)=O)CCC3)=O)CCC2
Molecular Formula
C26H37N5O7
Molecular Weight
531.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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