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KT2

Product Specifications

CAS Number

1539295-32-3

Target

Antibacterial, Antibiotic

Related Pathways

Microbiology/Virology

Bioactivity

KT2 is a cationic amphipathic antimicrobial peptide. It is capable of completely killing (E. coli) O157:H7 cells. KT2 exhibits strong antibiofilm activity, preventing the formation of E. coli O157:H7 biofilms. Additionally, KT2 effectively binds to LPS on bacterial surfaces, interacts with the lipids in liposomes, and displays high permeability, allowing it to penetrate bacterial cells and bind with DNA and other cytoplasmic membranes.

Smiles

C([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@H](C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N[C@@H](CC=5C=6C(NC5)=CC=CC6)C(N)=O)=O)=O)CCCCN)=O)CCCCN)=O)=O)NC([C@@H](NC([C@H](CC=7C=8C(NC7)=CC=CC8)NC([C@H](CC=9C=%10C(NC9)=CC=CC%10)NC([C@@H](NC([C@H](CC%11=CC=C(O)C=C%11)NC([C@@H](NC(=O)[C@H]%12N(C([C@@H](NC([C@@H](NC(CNC([C@H](CC(N)=O)N)=O)=O)C(C)C)=O)CCC(N)=O)=O)CCC%12)CCCCN)=O)=O)CCCCN)=O)=O)=O)CCCCN)=O)C=%13C=%14C(NC%13)=CC=CC%14

Molecular Formula

C126H165N31O20

Molecular Weight

2433.85

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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