Ac-IETD-AFC TFA
Product Specifications
Target
Caspase
Related Pathways
Proteases/Proteasome, Apoptosis
Bioactivity
Ac-IETD-AFC TFA is a synthetic fluorescent substrate used for the specific detection of Caspase-8 enzyme activity. It contains the fluorescent group AFC (7-amino-4-trifluoromethylcoumarin), which becomes free and emits fluorescence (Ex=~400 nm; Em=~505 nm) when Caspase-8 cleaves the amide bond following the IETD sequence. [INDO 1 pentasodium].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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