RANK-derived TRAF6 inhibitor
Product Specifications
CAS Number
1393741-66-6
Target
TNF
Related Pathways
Apoptosis
Bioactivity
RANK-derived TRAF6 inhibitor is a TRAF6 inhibitory peptide that blocks the interaction between TRAF6 and LMP1, with an IC50 of 177 nM. Furthermore, it significantly decreases the viability of LMP1-dependent lymphoblastoid cell lines (LCL) .
Smiles
C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=C(O)C=C5)C(O)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CCC4)[C@H](CC)C)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)CCSC)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)C=6C=7C(NC6)=CC=CC7
Molecular Formula
C158H250N48O40S
Molecular Weight
3494.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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