LS10

LS10 is a functional ligand that specifically binds to the NG2 protein, facilitating targeted drug delivery to gliomas. The NG2 protein is widely overexpressed in glioma cells, while its expression is limited in normal tissues.

C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)N)=O)[C@@H](C)O)=O)CC(C)C)=O)CCCNC(=N)N)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CCSC)=O)CC(C)C)=O)=O)C(C)C)=O)C=1C=2C(NC1)=CC=CC2