FNIII14

Product Specifications

CAS Number

206536-96-1

Target

Integrin

Related Pathways

Cytoskeletal Signaling

Bioactivity

FNIII14 is derived from the 14th type III-like (FN-III) repeat sequence of the fibronectin (FN) molecule. It inhibits cellular adhesion to the extracellular matrix (ECM) by inducing β1-integrin (β1integrin) to shift from an active to an inactive state, blocking integrin-mediated signaling. With its antifibrotic and anticancer properties, FNIII14 is useful for research in metabolic diseases, organ fibrosis, and malignancies.

Smiles

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