LNSMGQD
Product Specifications
CAS Number
1152066-26-6
Target
P38 MAPK
Related Pathways
MAPK
Bioactivity
LNSMGQD is a peptide that targets the adhesive interfaces of desmoglein (DSG1 and DSG3) core glycoproteins, interfering with the single peptide (SP) components of DSG trans-interactions. By binding to DSGs, LNSMGQD prevents the loss of DSG trans-interactions induced by autoantibodies, inhibits the activation of p38 MAPK, and prevents keratin filament retraction. It is useful for research into autoimmune skin diseases such as pemphigus vulgaris.
Smiles
[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)CCC(N)=O)=O)=O)CCSC)=O)CO)=O)(NC([C@H](CC(C)C)N)=O)CC(N)=O
Molecular Formula
C29H49N9O13S
Molecular Weight
763.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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