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AStAx-35R TFA

Product Specifications

Target

Wnt/beta-catenin

Related Pathways

Stem Cells, Cytoskeletal Signaling

Bioactivity

AStAx-35R TFA is a stapled peptide that antagonizes the nuclear form of β-catenin and inhibits Wnt signaling. It competitively inhibits the binding of β-catenin to TCF4. Furthermore, aStAx-35R TFA selectively induces growth inhibition in Wnt-dependent cancer cells.

Molecular Formula

C111H178N40O20.xC2HF3O2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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