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Cyclo (CKLIIF) TFA

Product Specifications

Target

HIF/HIF Prolyl-Hydroxylase

Related Pathways

Chromatin/Epigenetic, Metabolism

Bioactivity

Cyclo CKLIIF is a dual inhibitor of the hypoxia-inducible factors HIF1 and HIF2, effectively disrupting the interaction between HIF1-α and HIF2-α with HIF1-β. The dissociation constants (KD) for the PAS-B domains of HIF1-α and HIF2-α are 2.6 μM and 2.2 μM, respectively.

Molecular Formula

C38H60F3N7O8S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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