Klotho-derived peptide 1
Product Specifications
Target
TGF-beta/Smad, p38 MAPK
Related Pathways
Stem Cells, MAPK
Bioactivity
Klotho-derived peptide 1 (KP1 human) can inhibit the interaction between TGF-β and its receptor TGF-β receptor 2, suppressing the activation of Smad2/3 and mitogen-activated protein kinase (MAPK) induced by TGF-β. It shows anti-fibrotic and renal protective effects in mouse models.
Molecular Formula
C149H203N39O43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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