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Kiss2 peptide

Product Specifications

Target

PKC|||PKA|||Kisspeptin

Related Pathways

Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Chromatin/Epigenetic|||GPCR/G Protein

Bioactivity

Kiss2 peptide functions as a positive regulator of reproductive behavior. In COS-7 cells, it binds to its homologous G-protein coupled receptor Kiss2R (GPR54), activating the PKA and PKC signaling pathways through Gas and Gaq proteins. This enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) .

Smiles

C([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CC2=CC=CC=C2)N)=O)CC(N)=O)=O)=O)CC(N)=O)(=O)N3[C@H](C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)=O)CCC3