Cyclo (CRVIIF)
Product Specifications
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic, Metabolism
Bioactivity
Cyclo CRVIIF is a dual inhibitor of hypoxia-inducible factors HIF1 and HIF2. It disrupts the interaction between HIF1-α, HIF2-α, and HIF1-β, with dissociation constants (KD) for the PAS-B domains of HIF1-α and HIF2-α measured at 65 and 123 μM, respectively.
Molecular Formula
C35H57N9O6S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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