Cyclo (CRLLIF)
Product Specifications
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Metabolism, Chromatin/Epigenetic
Bioactivity
Cyclo CRLLIF serves as a dual inhibitor of hypoxia-inducible factors HIF1 and HIF2, disrupting the interaction between HIF1-α and HIF2-α with HIF1-β. It exhibits dissociation constants (KD) of 14.5 μM for HIF1-α and 10.2 μM for HIF2-α within the PAS-B domains.
Molecular Formula
C36H59N9O6S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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