PAR3 (1-6) (human)
Product Specifications
CAS Number
320347-28-2
Target
Protease-activated Receptor
Related Pathways
GPCR/G Protein
Bioactivity
PAR3 (1-6) is a synthetic peptide agonist of Protease-Activated Receptor 1 (PAR1), corresponding to residues 1-6 of the extracellular tethered ligand sequence from human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates the p42/44 MAPK signaling pathway in fibroblasts expressing PAR1 but not PAR3. This activation can be inhibited by the PAR1 antagonist RWJ 56110.1.
Smiles
C([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H]([C@@H](C)O)N)=O)=O)CCCNC(=N)N)=O)=O)C)(=O)N2[C@H](C(O)=O)CCC2
Molecular Formula
C29H45N9O8
Molecular Weight
647.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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