(S, S) -Z-FA-FMK
Product Specifications
CAS Number
105637-38-5
Target
Cysteine Protease
Related Pathways
Proteases/Proteasome
Bioactivity
(S, S) -Z-FA-FMK is a cell-permeable, irreversible inhibitor of cathepsin B. This compound inhibits the production of IL-1α and IL-1β induced by LPS. Additionally, (S, S) -Z-FA-FMK serves as a negative control for caspase-1 and caspase-2 inhibitors due to the absence of an aspartic acid residue at the P1 position.
Smiles
[C@H](CC1=CC=CC=C1)(C(N[C@H](C(CF)=O)C)=O)NC(OCC2=CC=CC=C2)=O
Molecular Formula
C21H23FN2O4
Molecular Weight
386.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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