RI-STAD-2
Product Specifications
Target
PKA
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
RI-STAD-2 is a high-affinity peptide that interferes with the regulatory subunit RI of protein kinase A (PKA) . It disrupts the binding between A-kinase anchoring proteins (AKAPs) and PKA-RI by mimicking the α-helical domain of AKAPs, interacting with the dimerization/docking (D/D) domain of PKA-RI. This disruption affects the activity and intracellular localization of PKA. RI-STAD-2 is utilized in studying the role of AKAPs and PKA-RI interactions in pathological processes such as cardiovascular diseases and cancer.
Molecular Formula
C109H181N25O35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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