AQP4 (205-215)

Product Specifications

CAS Number

2891466-35-4

Target

Aquaporin

Related Pathways

Membrane transporter/Ion channel

Bioactivity

AQP4 (205-215) is a fragment of the water channel protein Aquaporin-4 (AQP4) . This protein is an autoimmune antigen in optic neuromyelitis and, upon binding with CD40, is upregulated and presented in B cells. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS) .

Smiles

C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)=O)C)=O)CO)=O)CCSC)=O)CC(N)=O)(=O)N2[C@H](C(N[C@H](C(O)=O)C)=O)CCC2