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IETP2

Product Specifications

CAS Number

2314338-36-6

Target

LDLR

Related Pathways

Metabolism

Bioactivity

IETP2 targets low-density lipoprotein receptor-related protein 1 (LRP1) with a KD of 738 nM, making it useful for delivering drugs and imaging agents across the blood-labyrinth barrier (BLB) .

Smiles

C([C@@H](NC(CNC(CNC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC2=CC=CC=C2)NC([C@H]([C@@H](C)O)N)=O)=O)=O)=O)=O)CCCNC(=N)N)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC(O)=O)C(O)=O)=O)=O)CCCNC(=N)N)=O)CO)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)CC(N)=O)=O)CC(N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCC3