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TAT-N15

Product Specifications

CAS Number

2415370-74-8

Target

NF-κB, Akt, STAT, Interleukin

Related Pathways

JAK/STAT signaling, Cytoskeletal Signaling, Immunology/Inflammation, PI3K/Akt/mTOR signaling, NF-κB, Stem Cells

Bioactivity

TAT-N15, a p55PIK inhibitor, demonstrates significant anti-inflammatory and neuroprotective effects. It effectively suppresses the activation of IL-6, IL-8, Akt, and NF-κB pathways, along with the phosphorylation of STAT3 and the protein expression of NF-κB. TAT-N15 is applicable for research on acute conjunctivitis, allergic rhinitis, chronic obstructive pulmonary disease (COPD), and stroke through its inhibition of Akt, STAT3, and NF-κB pathways.

Smiles

C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(O)=O)CCC4)CC(O)=O)=O)CCSC)=O)CCC(O)=O)=O)[C@H](CC)C)=O)=O)=O)[C@H](CC)C)=O)CC(C)C)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CO)=O)(=O)[C@H]5N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC6=CC=C(O)C=C6)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCSC)=O)CCSC)=O)CCC5

Molecular Formula

C155H250N48O40S3

Molecular Weight

3522.14

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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