Corza6
Product Specifications
Target
ROS, Proton pump, Reactive Oxygen Species
Related Pathways
Membrane transporter/Ion channel, Immunology/Inflammation, NF-κB, Metabolism
Bioactivity
Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1) . It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC) .
Molecular Formula
C203H293N55O61S7
Molecular Weight
4704.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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