Pep1-DNP conjugate 9
Product Specifications
Target
Apoptosis, FGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis
Bioactivity
Pep1-DNP conjugate 9 is a functionalized peptide composed of a DNP-hapten and an FGFR1-binding peptide. It exhibits good affinity for FGFR1, with a dissociation constant (KD) of 5.01 μM. This compound effectively recruits anti-DNP antibodies to the surface of FGFR1-positive cells, inhibits FGF2-induced proliferation of rat skeletal myoblasts, and induces apoptosis. In mouse models, Pep1-DNP conjugate 9 demonstrates antitumor activity.
Molecular Formula
C135H207N37O41
Molecular Weight
3004.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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