Vaccarin C
Product Specifications
CAS Number
177602-12-9
Target
Antifungal
Related Pathways
Microbiology/Virology
Bioactivity
Vaccarin C (Compound VIII) is a cyclic heptapeptide with significant antifungal activity, demonstrating a MIC of 6 µg/mL against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes. It also exhibits high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich ascites carcinoma (EAC) cell lines, with CTC50 values of 3.35 and 5.72 ?mol/L, respectively.
Smiles
C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N4[C@@](CCC4)(C(=O)NCC(=O)N[C@@H](CC5=CC=C(O)C=C5)C(=O)N[C@@H]([C@@H](C)C)C(=O)N6[C@](C(=O)N[C@@H](CC(C)C)C(=O)N3)(CCC6)[H])[H]
Molecular Formula
C43H56N8O8
Molecular Weight
812.953
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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