Cyclic (YCDGFYACYMDV)

Cyclic (YCDGFYACYMDV) is a HER2 signaling pathway inhibitor with anticancer properties. In aqueous solution, Cyclic (YCDGFYACYMDV) self-assembles into nanoparticles that target HER2 on cancer cells, converting into nanofibrils. This process disrupts HER2 dimerization and subsequent downstream signaling, leading to apoptosis (Apoptosis) of cancer cells. Its inhibitory effect on HER2-positive breast cancer has been demonstrated as effective in mouse xenograft models.

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