Pegtarazimod
Product Specifications
CAS Number
2056232-82-5
Target
Reactive Oxygen Species, ROS
Related Pathways
Metabolism, NF-κB, Immunology/Inflammation
Bioactivity
Pegtarazimod (RLS-0071) inhibits the complement system through both the classical and lectin pathways. It suppresses myeloperoxidase (MPO) activity, leading to reduced ROS production, and decreases the formation of neutrophil extracellular traps (NET) . Pegtarazimod exhibits anti-inflammatory properties and is applicable in the study of acute graft-versus-host disease.
Smiles
CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O)N
Molecular Formula
C122H224N20O46S2
Molecular Weight
2771.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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