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Poneratoxin acetate

Product Specifications

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.

Smiles

[H]N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(N[C@H](C(N[C@]([H])(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N[C@]([H])(C(N3CCC[C@H]3C(N4CCC[C@H]4C(N[C@H](C(N[C@]([H])(C(N[C@H](C(N[C@@H](C)C(N[C@]([H])(C(N[C@@H](CC5=CN=CN5)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)=O)=O)=O)[C@@H](C)CC)=O)=O)CCC(N)=O)=O)[C@@H](C)CC)=O)C(C)C)=O)=O)=O)[C@H](O)C)=O)=O)CC(C)C)=O)CC(C)C)=O)CO)=O)=O)CC(C)C)=O)[C@@H](C)CC)=O)CC(C)C)=O)CC(C)C)=O)=O)CC(C)C)=O.CC(O)=O

Molecular Formula

C129H215N33O31S.xC2H4O2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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