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McK6A1

Product Specifications

Target

Beta Amyloid

Related Pathways

Neuroscience

Bioactivity

McK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.

Smiles

C[C@H]([C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCCC[C@@H](C(=O)NNC(=O)C2=C(C=CC(=C2)NC(=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)NCCC[C@@H](C(=O)N1)N)CC3=CC=C(C=C3)O)CCCCN)OC)N)CCCCN)CC4=CC=C(C=C4)O)CC5=CNC6=CC=CC=C65)CC(C)C)O

Molecular Formula

C71H99N17O16

Molecular Weight

1446.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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