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Bicyclic UK18

Product Specifications

CAS Number

1393680-45-9

Target

PAI-1

Related Pathways

Metabolism

Bioactivity

Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.

Smiles

C([C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@]2(C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(NCC(O)=O)=O)CSCC3=CC(CSC[C@H](NC([C@H](C)N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1)=CC(CSC2)=C3)[H])C4=CC=C(O)C=C4

Molecular Formula

C77H118N26O25S3

Molecular Weight

1904.11

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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