VU0506013
Product Specifications
CAS Number
1207036-87-0
Target
Neuropeptide Y Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
VU0506013 is a high-affinity positive allosteric modulator (PAM) of the neuropeptide Y4 receptor. This compound demonstrates nanomolar-level affinity and notable selectivity in engineered cell lines and the descending colon mucosa of mice that naturally express Y4R. VU0506013 presents a promising foundation for developing in vivo tools aimed at advancing anti-obesity compound research targeting Y4R.
Smiles
O=C(C=1C=C(NC(=O)COC=2C=CC=CC2C)C(=O)N(C1)C)N3CCCC3
Molecular Formula
C20H23N3O4
Molecular Weight
369.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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