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VU0506013

Product Specifications

CAS Number

1207036-87-0

Target

Neuropeptide Y Receptor

Related Pathways

Neuroscience|||GPCR/G Protein

Bioactivity

VU0506013 is a high-affinity positive allosteric modulator (PAM) of the neuropeptide Y4 receptor. This compound demonstrates nanomolar-level affinity and notable selectivity in engineered cell lines and the descending colon mucosa of mice that naturally express Y4R. VU0506013 presents a promising foundation for developing in vivo tools aimed at advancing anti-obesity compound research targeting Y4R.

Smiles

O=C(C=1C=C(NC(=O)COC=2C=CC=CC2C)C(=O)N(C1)C)N3CCCC3

Molecular Formula

C20H23N3O4

Molecular Weight

369.41

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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