BMP-4
Product Specifications
CAS Number
1629625-47-3
Target
COX|||Interleukin|||IFNAR
Related Pathways
Neuroscience|||Immunology/Inflammation
Bioactivity
BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 through modulation of the iNOS-IFN-IL6 signaling pathway.
Smiles
C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CS)=O)CC(N)=O)(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)CCC2
Molecular Formula
C52H93N25O13S
Molecular Weight
1308.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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