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BMP-4

Product Specifications

CAS Number

1629625-47-3

Target

COX|||Interleukin|||IFNAR

Related Pathways

Neuroscience|||Immunology/Inflammation

Bioactivity

BMP-4, a heparin-binding peptide, exhibits anti-inflammatory and anti-chondrogenic properties. In murine chondrocytes and macrophages, it effectively mitigates inflammation and alleviates symptoms of various arthritides by dose-dependently suppressing the expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6 through modulation of the iNOS-IFN-IL6 signaling pathway.

Smiles

C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CS)=O)CC(N)=O)(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)CCC2

Molecular Formula

C52H93N25O13S

Molecular Weight

1308.52

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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