Macrophage-activating lipopeptide 2 TFA

Product Specifications

Target

IL Receptor|||Prostaglandin Receptor|||TLR|||TNF|||NO Synthase

Related Pathways

Apoptosis|||GPCR/G Protein|||Immunology/Inflammation

Purity

0.9756

Bioactivity

Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist that activates immune cell responses such as macrophages, upregulating TNF, IL-6, and PGE2 to induce local inflammation.

Smiles

NC(C[C@@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@]([H])(C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CCC(O)=O)=O)CCCCN)=O)=O)CO)=O)[C@@H](C)CC)=O)CC(N)=O)=O)CO)=O)CCC(O)=O)=O)=O)CC(N)=O)=O)NC(CNC([C@H](N)CSC[C@H](COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCC)=O)=O)=O)=O.OC(C(F)(F)F)=O