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EC-1456

Product Specifications

CAS Number

1602487-16-0

Target

Others, Antifolate

Related Pathways

Cell Cycle/Checkpoint, Others

Bioactivity

EC-1456 is a folate-microtubule targeting agent that exhibits significant antiproliferative activity against folate receptor (FR) positive tumors, including models resistant to anticancer drugs. EC-1456 is utilized in cancer research.

Smiles

[C@H](C[C@@H](N(C([C@@H](NC(=O)[C@@H]1N(C)CCCC1)[C@H](CC)C)=O)COC(CCC)=O)C(C)C)(OC(C)=O)C2=NC(C(N[C@@H](CC3=CC=C(O)C=C3)C[C@@H](C(NNC(OCCSSC[C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@@H](NC(CC[C@@H](NC(=O)C4=CC=C(NCC=5N=C6C(NC5)=NC(N)=NC6=O)C=C4)C(O)=O)=O)CCC(NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)CCC(O)=O)=O)CCC(NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)CCC(O)=O)=O)CCC(NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)C(O)=O)=O)=O)C)=O)=CS2

Molecular Formula

C110H165N23O45S3

Molecular Weight

2625.81

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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