GSK3β-peptide

GSK3β-peptide is a substrate mimetic peptide of glycogen synthase kinase 3-beta (GSK3-β) that binds to the active site of GSK3-β, simulating the behavior of actual substrates. It serves as a basis for developing substrate analog inhibitors of Akt, with potential applications as anticancer compounds.

C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)C)=O)=O)CO)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CCCNC(=N)N)(=O)[C@H]2N(C([C@H](CCCNC(=N)N)NC(CN)=O)=O)CCC2