AAV-8 NSL epitope

The AAV-8 NSL epitope, isolated from the capsid of serotype 8 of an adeno-associated virus (AAV), exhibits high affinity for MHC I molecules, enabling it to bind with MHC I and subsequently activate CD8+ T cells. This epitope is instrumental in researching the impact of T cell-mediated immune responses on AAV-mediated gene transfer.

C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(N)=O)N)=O)CO)=O)CC(C)C)=O)C)=O)CC(N)=O)(=O)N1[C@H](C(NCC(N[C@H](C(N[C@H](C(O)=O)C)=O)[C@H](CC)C)=O)=O)CCC1