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SmMLCK peptide

Product Specifications

CAS Number

172960-20-2

Target

Myosin

Related Pathways

Cytoskeletal Signaling

Bioactivity

The smMLCK peptide is a specific inhibitor of smooth muscle myosin light chain kinase (smMLCK) . It functions by mimicking the substrate and competitively inhibiting the binding of the natural substrate to the enzyme, thereby reducing kinase activity. This inhibition prevents the phosphorylation of the myosin light chain, which subsequently impedes muscle contraction.

Smiles

C([C@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC([C@H](C)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CO)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)[C@H](CC)C)=O)C)=O)CCCNC(=N)N)=O)C(C)C)=O)C)=O)=O)=O)[C@@H](C)O)=O)CCCCN)=O)CCC(N)=O)=O)C=2C=3C(NC2)=CC=CC3

Molecular Formula

C98H168N38O25

Molecular Weight

2278.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/217697283330801685/TP2657

Available Sizes

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