LIH383
Product Specifications
CAS Number
2866266-58-0
Target
CXCR
Related Pathways
Immunology/Inflammation, Autophagy, GPCR/G Protein
Bioactivity
LIH383, an agonist of ACKR3 (CXCR7) with an EC50 of 0.61 nM, effectively promotes the recruitment of β-arrestin to ACKR3. However, it does not initiate typical G protein signaling.
Smiles
[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCSC)=O)NC(CNC(CNC([C@H](CC2=CC=CC=C2)N)=O)=O)=O
Molecular Formula
C45H72N16O8S
Molecular Weight
997.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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