Serpinin
Product Specifications
CAS Number
1383743-23-4
Bioactivity
Serpinin, an agonist of the protease inhibitor Nexin-1 (PN-1), upregulates PN-1 expression via the cAMP-PKA-Sp1 signaling pathway, facilitating granule biogenesis in endocrine cells. It is employed in research on secretory function regulation [1]. Serpinin selectively targets β-adrenergic receptors, particularly interacting with β1-adrenergic receptors to activate the AC-cAMP-PKA pathway, thereby regulating myocardial systolic and diastolic function. Additionally, pGlu-serpinin upregulates Bcl2 mRNA transcription and provides neuroprotective effects [2].
Smiles
[C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C)=O)CCC(N)=O)=O)CC(C)C)=O)CCC(N)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]2CCCN2)CCC(O)=O)=O)CC(O)=O)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CO)=O)CC(C)C)=O)CO)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)C)=O)CCC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCCCN)=O)C(C)C)=O)C)=O
Molecular Formula
C125H204N32O46
Molecular Weight
2891.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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