Nanrilkefusp alfa

Nanrilkefusp alfa (SO-C101; SOT101), a fusion protein, serves as a powerful and selective agonist of the IL-15 and IL-15Rα sushi + domain. It promotes the proliferation and activation of memory CD8 + T cells, natural killer (NK) cells, γ/δ T cells, and NKT cells to inhibit tumor growth. Nanrilkefusp alfa demonstrates remarkable anti-metastatic effects in melanoma and effectively suppresses tumor progression in various mouse tumor models [1] [2].