FZD7 antagonist 1
Product Specifications
CAS Number
2416664-25-8
Target
Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling, Stem Cells
Bioactivity
FZD7 antagonist 1 (peptide 34), a dFz7-21 analogue, inhibits wnt3a with an IC50 of 9.2 nM and blocks TcdB−FZD interaction by targeting FZD receptors [1].
Smiles
C([C@@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N)=O)=O)CCSC)=O)[C@H](CC)C)=O)=O)CSSC[C@H](NC([C@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)[C@@H](C)O)=O)CC(O)=O)=O)CC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CC(C)C)=O)=O)C(N[C@@H](CC5=CN=CN5)C(N[C@H](C(N[C@H](C(N[C@@H](CC6=CC=C(O)C=C6)C(N)=O)=O)CCSC)=O)[C@H](CC)C)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)[C@@H](C)O)=O)CC(O)=O)=O)CC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CC(C)C)=O)C=7C=8C(NC7)=CC=CC8
Molecular Formula
C142H202N32O42S4
Molecular Weight
3157.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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