(Trp63, Trp64) ​-​C3a (63-77)

(Trp63, Trp64) ​-C3a (63-77) is a C3a synthetic analogue peptide that exhibits Ca 2+ stimulating efficacy in human neutrophils, as well as hC3aR or mC3aR expressing RBL-2H3 cells, with EC50 values of 9.5, 2.0, and 0.8 nM, respectively [1].

C([C@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)N)=O)C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)C)=O)CC(C)C)=O)=O)CC(C)C)=O)CCCCN)=O)CO)=O)C)=O)CCCNC(=N)N)=O)=O)CCCCN)=O)CCCCN)=O)=O)C=4C=5C(NC4)=CC=CC5