Dutomycin
Product Specifications
CAS Number
146663-67-4
Target
Autophagy|||Apoptosis
Related Pathways
Autophagy|||Apoptosis
Bioactivity
Dutomycin is a SERPINB6 inhibitor with a binding constant (KD) of 1.236 ?M. It can induce autophagy and apoptosis in cancer cells and suppresses the growth of cancer cells in zebrafish xenotransplant models. Dutomycin holds potential for cancer research.
Smiles
O[C@]12[C@](O)(C(=O)C=3C(C1)=C(C)C4=C(C3O)C(=O)C=C(OC)C4=O)C(=O)C(C(C)=O)=C(O)[C@H]2O[C@@H]5O[C@H](C)[C@@H](O[C@H]6C[C@@](C)(O)[C@H](OC(/C(=C\[C@@H](CCC)C)/C)=O)[C@H](C)O6)CC5
Molecular Formula
C44H54O17
Molecular Weight
854.889
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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